
After underlining the accord amid efficacy, toxicity and biologic concentration, the book again considers how metabolizing systems accomplish and how they appulse aloft biologic concentration, both beneath biologic burden and during inhibition. Factors affecting biologic metabolism, such as abiogenetic polymorphisms, age and diet are discussed and how metabolism can advance to toxicity is explained. The book concludes with the role of biologic metabolism in the bartering development of ameliorative agents as able-bodied as the pharmacology of some adulterous drugs.
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